In addition to the risk of developing opioid use disorder oud long term opioid use has been shown to cause chronic inflammation and hyperalgesia suggesting that opioids may induce an immune.
Chronic opioid use side effects.
Hypersensitivity to pain caused by opioid use which causes the nervous system to become overly sensitive.
Other long term effects of opioid use include.
A disorder also known as delayed gastric emptying which slows or stops the movement of food from the.
The most common being gastrointestinal problems like constipation nausea and vomiting.
B systematic review of low quality studies.
B 2 observational studies.
Less common side effects of opioid use may include.
Common side effects of opioid administration include sedation dizziness nausea vomiting constipation physical dependence tolerance and respiratory depression.
Physical dependence and addiction are clinical concerns that may prevent proper prescribing and in turn inadequate pain management.
Addiction irregular heart beat increased risk of heart attack depression constipation severe abdominal pain hormonal problems weak bones increased pain.
Constipation nausea and dyspepsia are the most common long term adverse effects of chronic opioid use strength of recommendation sor.